Martine Rothblatt – Net worth: $600 million
Martine Rothblatt’s first tasted success in 1990, when she founded the popular radio station Sirius Satellite Radio. After her daughter was diagnosed with a fatal disease, however, Rothblatt pivoted to biotech.

Rothblatt founded United Therapeutics, a company which remains at the cuttingedge of medical science, helping Rothblatt build a $600 million fortune.